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Inorganic acids, or mineral acids, are highly corrosive, water-soluble, and derived from inorganic compounds. Available in a range of chemical compositions and acid strengths, they can be used for syntheses of organic and inorganic chemicals.
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ARD-1676 is an orally active androgen receptor (AR) proteolysis-targeting chimera (PROTAC) that links an AR ligand to a cereblon ligand to induce targeted degradation of AR. It shows potent AR-degrading activity in vitro and in vivo and suppresses tumor growth in AR-driven VCaP xenograft models.
Orally active PROTAC degrader targeting the androgen receptor.
Demonstrated AR degradation in vitro and efficacy in vivo.
High reported purity (~99.36%).
Molecular weight approximately 788.33 Da.
Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
Storage recommendations: refrigerated; in solvent, -80°C (6 months) or -20°C (1 month), protect from light.
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